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Regulation of Proinflammatory Molecules and Tissue Factor by SARS-CoV-2 Spike Protein in Human Placental Cells: Implications for SARS-CoV-2 Pathogenesis in Pregnant Women

SARS-CoV-2 infects cells via binding to ACE2 and TMPRSS2, which allows the virus to fuse with host cells. The viral RNA is detected in the placenta of SARS-CoV-2-infected pregnant women and infection is associated with adverse pregnancy complications. Therefore, we hypothesize that SARS-CoV-2 infect...

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Detalles Bibliográficos
Autores principales:	Guo, Xiaofang, Semerci, Nihan, De Assis, Viviana, Kayisli, Umit A., Schatz, Frederick, Steffensen, Thora S., Guzeloglu-Kayisli, Ozlem, Lockwood, Charles J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022221/ https://www.ncbi.nlm.nih.gov/pubmed/35464466 http://dx.doi.org/10.3389/fimmu.2022.876555

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