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5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection

OBJECTIVE: Universal noninvasive genomic screening to detect cancer and/or fetal DNA in plasma at all stages of development is highly warranted. Since 5-hydroxymethylcytosine (5hmC) emerged as an intermediate metabolite in active DNA demethylation, there have been increasing efforts to elucidate its...

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Detalles Bibliográficos
Autores principales: Lu, Michael J., Lu, Yabin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022237/
https://www.ncbi.nlm.nih.gov/pubmed/35449110
http://dx.doi.org/10.1186/s13104-022-06028-w