Optimization of levetiracetam dosing regimen in critically ill patients with augmented renal clearance: a Monte Carlo simulation study

BACKGROUND: Levetiracetam pharmacokinetics is extensively altered in critically ill patients with augmented renal clearance (ARC). Consequently, the dosage regimens commonly used in clinical practice may not be sufficient to achieve target plasma concentrations. The aim of this study is to propose a...

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Detalles Bibliográficos
Autores principales: Bilbao-Meseguer, Idoia, Barrasa, Helena, Rodríguez-Gascón, Alicia, Asín-Prieto, Eduardo, Maynar, Javier, Sánchez-Izquierdo, José Ángel, Solinís, María Ángeles, Isla, Arantxazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022299/
https://www.ncbi.nlm.nih.gov/pubmed/35449037
http://dx.doi.org/10.1186/s40560-022-00611-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022299/
https://www.ncbi.nlm.nih.gov/pubmed/35449037
http://dx.doi.org/10.1186/s40560-022-00611-w

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