Preclinical Immunogenicity and Efficacy of Optimized O25b O-Antigen Glycoconjugates To Prevent MDR ST131 E. coli Infections

Multivalent O-antigen polysaccharide glycoconjugate vaccines are under development to prevent invasive infections caused by pathogenic Enterobacteriaceae. Sequence type 131 (ST131) Escherichia coli of serotype O25b has emerged as the predominant lineage causing invasive multidrug-resistant extrainte...

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Detalles Bibliográficos
Autores principales: Chorro, Laurent, Li, Zhenghui, Chu, Ling, Singh, Suddham, Gu, Jianxin, Kim, Jin-hwan, Dutta, Kaushik, Pan, Rosalind, Kodali, Srinivas, Ndreu, Duston, Patel, Axay, Hawkins, Julio C., Ponce, Chris, Silmon de Monerri, Natalie, Keeney, David, Illenberger, Arthur, Jones, C. Hal, Andrew, Lubomira, Lotvin, Jason, Prasad, A. Krishna, Kanevsky, Isis, Jansen, Kathrin U., Anderson, Annaliesa S., Donald, Robert G. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Bacterial Infections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022517/
https://www.ncbi.nlm.nih.gov/pubmed/35311580
http://dx.doi.org/10.1128/iai.00022-22

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