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Characterization of the Phase-Variable Autotransporter Lav Reveals a Role in Host Cell Adherence and Biofilm Formation in Nontypeable Haemophilus influenzae

Lav is an autotransporter protein found in pathogenic Haemophilus and Neisseria species. Lav in nontypeable Haemophilus influenzae (NTHi) is phase-variable: the gene reversibly switches ON-OFF via changes in length of a locus-located GCAA((n)) simple DNA sequence repeat tract. The expression status...

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Detalles Bibliográficos
Autores principales:	Phillips, Zachary N., Garai, Preeti, Tram, Greg, Martin, Gael, Van Den Bergh, Annelies, Husna, Asma-Ul, Staples, Megan, Grimwood, Keith, Jennison, Amy V., Guillon, Patrice, von Itzstein, Mark, Jennings, Michael P., Brockman, Kenneth L., Atack, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Molecular Pathogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022572/ https://www.ncbi.nlm.nih.gov/pubmed/35258316 http://dx.doi.org/10.1128/iai.00565-21

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