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TTLL1 and TTLL4 polyglutamylases are required for the neurodegenerative phenotypes in pcd mice

Polyglutamylation is a dynamic posttranslational modification where glutamate residues are added to substrate proteins by 8 tubulin tyrosine ligase-like (TTLL) family members (writers) and removed by the 6 member Nna1/CCP family of carboxypeptidases (erasers). Genetic disruption of polyglutamylation...

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Detalles Bibliográficos
Autores principales:	Wu, Hui-Yuan, Rong, Yongqi, Bansal, Parmil K., Wei, Peng, Guo, Hong, Morgan, James I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022812/ https://www.ncbi.nlm.nih.gov/pubmed/35404950 http://dx.doi.org/10.1371/journal.pgen.1010144

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