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A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase

The highly conserved, cardiotonic steroid binding site (also termed ouabain binding site) on the primary α subunit of Na,K-ATPase plays a receptor signaling role in a range of vital cell processes and is a therapeutic target for human disease. Mouse lines with altered affinity for cardiotonic steroi...

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Detalles Bibliográficos
Autores principales:	Chomczynski, Peter W., Vires, Kianna M., Rymaszewski, Michal, Heiny, Judith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Lab Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022855/ https://www.ncbi.nlm.nih.gov/pubmed/35446892 http://dx.doi.org/10.1371/journal.pone.0267348

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