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Multiple roles of Pol epsilon in eukaryotic chromosome replication

Pol epsilon is a tetrameric assembly that plays distinct roles during eukaryotic chromosome replication. It catalyses leading strand DNA synthesis; yet this function is dispensable for viability. Its non-catalytic domains instead play an essential role in the assembly of the active replicative helic...

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Detalles Bibliográficos
Autores principales:	Cvetkovic, Milos A., Ortega, Esther, Bellelli, Roberto, Costa, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2022
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022971/ https://www.ncbi.nlm.nih.gov/pubmed/35129614 http://dx.doi.org/10.1042/BST20210082

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