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Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway
Programmed cell death has long been characterised as a key player in the development of human disease. Necroptosis is a lytic form of programmed cell death that is universally mediated by the effector protein mixed lineage kinase domain-like (MLKL), a pseudokinase. MLKL's activating kinase, rec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022980/ https://www.ncbi.nlm.nih.gov/pubmed/35166320 http://dx.doi.org/10.1042/BST20210517 |