Pinpointing the tumor-specific T cells via TCR clusters

Adoptive cell transfer (ACT) is a promising approach to cancer immunotherapy, but its efficiency fundamentally depends on the extent of tumor-specific T cell enrichment within the graft. This can be estimated via activation with identifiable neoantigens, tumor-associated antigens (TAAs), or living o...

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Detalles Bibliográficos
Autores principales: Goncharov, Mikhail M, Bryushkova, Ekaterina A, Sharaev, Nikita I, Skatova, Valeria D, Baryshnikova, Anastasiya M, Sharonov, George V, Karnaukhov, Vadim, Vakhitova, Maria T, Samoylenko, Igor V, Demidov, Lev V, Lukyanov, Sergey, Chudakov, Dmitriy M, Serebrovskaya, Ekaterina O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023053/
https://www.ncbi.nlm.nih.gov/pubmed/35377314
http://dx.doi.org/10.7554/eLife.77274

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