Cargando…

Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells

Platelets are hyperactivated in coronavirus disease 2019 (COVID-19). However, the mechanisms promoting platelet activation by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not well understood. This may be due to inherent challenges in discriminating the contribution of viral vs ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Puhm, Florian, Allaeys, Isabelle, Lacasse, Emile, Dubuc, Isabelle, Galipeau, Yannick, Zaid, Younes, Khalki, Loubna, Belleannée, Clemence, Durocher, Yves, Brisson, Alain R., Wolberg, Alisa S., Langlois, Marc-André, Flamand, Louis, Boilard, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Platelets and Thrombopoiesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023084/ https://www.ncbi.nlm.nih.gov/pubmed/35443030 http://dx.doi.org/10.1182/bloodadvances.2022007444

Ejemplares similares

The fate of mitochondria during platelet activation
por: Grichine, Alexei, et al.
Publicado: (2023)

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis
por: Senis, Yotis A., et al.
Publicado: (2009)

Platelet activation and partial desensitization are associated with viral xenophagy in patients with severe COVID-19
por: Garcia, Cédric, et al.
Publicado: (2022)

Individual phosphatidylinositol transfer proteins have distinct functions that do not involve lipid transfer activity
por: Zhao, Liang, et al.
Publicado: (2023)

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
por: Hottz, Eugenio D., et al.
Publicado: (2020)

Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis
por: Kalot, Mohamad A., et al.
Publicado: (2022)

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP
por: Shao, Bojing, et al.
Publicado: (2022)

Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice
por: Englert, Maximilian, et al.
Publicado: (2022)

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins
por: O'Connor, Marie N., et al.
Publicado: (2009)

Platelet gene expression and function in patients with COVID-19
por: Manne, Bhanu Kanth, et al.
Publicado: (2020)

COVID-19 concerns aggregate around platelets
por: Battinelli, Elisabeth M.
Publicado: (2020)

Antibody-induced procoagulant platelets in severe COVID-19 infection
por: Althaus, Karina, et al.
Publicado: (2021)

Upregulation of cAMP prevents antibody-mediated thrombus formation in COVID-19
por: Zlamal, Jan, et al.
Publicado: (2022)

Low-dose decitabine modulates T-cell homeostasis and restores immune tolerance in immune thrombocytopenia
por: Han, Panpan, et al.
Publicado: (2021)

Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets
por: Bye, Alexander P., et al.
Publicado: (2021)

SARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP
por: Lee, Eun-Ju, et al.
Publicado: (2022)

Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
por: Greinacher, Andreas, et al.
Publicado: (2021)

Sugar and spike: not so nice
por: McKenzie, Steven E.
Publicado: (2021)

Iron status influences the response of cord blood megakaryocyte progenitors to eltrombopag in vitro
por: Liu, Zhi-Jian, et al.
Publicado: (2021)

The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production
por: Heazlewood, Shen Y., et al.
Publicado: (2022)

Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry
por: Kemble, Samuel, et al.
Publicado: (2022)

Platelet SHARPIN regulates platelet adhesion and inflammatory responses through associations with αIIbβ3 and LUBAC
por: Kasirer-Friede, Ana, et al.
Publicado: (2022)

Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19
por: Hottz, Eugenio D., et al.
Publicado: (2022)

The interaction between anti-PF4 antibodies and anticoagulants in vaccine-induced thrombotic thrombocytopenia
por: Singh, Anurag, et al.
Publicado: (2022)

G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1
por: Downes, Kate, et al.
Publicado: (2022)

A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD
por: Bury, Loredana, et al.
Publicado: (2022)

COVID-19 vaccination in patients with immune thrombocytopenia
por: Visser, Chantal, et al.
Publicado: (2022)

Evans syndrome in adults: an observational multicenter study
por: Fattizzo, Bruno, et al.
Publicado: (2021)

Expanding the genetic spectrum of TUBB1-related thrombocytopenia
por: Palma-Barqueros, Verónica, et al.
Publicado: (2021)

Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia
por: Kaur, Manraj N., et al.
Publicado: (2022)

Multiparameter phenotyping of platelet reactivity for stratification of human cohorts
por: Dunster, Joanne L., et al.
Publicado: (2021)

Blood–brain barrier permeability in survivors of immune-mediated thrombotic thrombocytopenic purpura: a pilot study
por: Huang, Shih-Han Susan, et al.
Publicado: (2021)

A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency
por: Fujii, Yoritaka, et al.
Publicado: (2021)

Abnormalities of bone marrow B cells and plasma cells in primary immune thrombocytopenia
por: Yu, Tian-shu, et al.
Publicado: (2021)

Platelet variability index: a measure of platelet count fluctuations in patients with immune thrombocytopenia
por: Li, Na, et al.
Publicado: (2021)

Bone marrow remodeling supports hematopoiesis in response to immune thrombocytopenia progression in mice
por: Herd, Oliver J., et al.
Publicado: (2021)

Ablation of collagen VI leads to the release of platelets with altered function
por: Abbonante, Vittorio, et al.
Publicado: (2021)

Assessment of romiplostim immunogenicity in pediatric patients in clinical trials and in a global postmarketing registry
por: Bowers, Charles, et al.
Publicado: (2021)

Platelet FcγRIIA-induced serotonin release exacerbates the severity of transfusion-related acute lung injury in mice
por: El Mdawar, Marie-Belle, et al.
Publicado: (2021)

Heparin or nonheparin anticoagulants for VITT
por: Arnold, Donald M.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_33is6tci6bcrvrl287b0uodans