Cargando…

Integrated Network Pharmacology and UPLC/Q-TOF-MS Screen System to Exploring Anti-Inflammatory Active Components and Mechanism of Shunaoxin Pills

BACKGROUND: Chronic cerebral ischemia (CCI) is a pathological condition associated with a variety of cerebrovascular diseases. Shunaoxin pills (SNX) are a traditional Chinese medicine (TCM) used to improve blood circulation. However, its multicomponent and multitarget features make it difficult to d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Nianwei, Wang, Yu, Jiang, Min, Bai, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023156/ https://www.ncbi.nlm.nih.gov/pubmed/35463086 http://dx.doi.org/10.1155/2022/2868767

Ejemplares similares

The role of Shunaoxin pills in the treatment of chronic cerebral hypoperfusion and its main pharmacodynamic components
por: Zhang, Jin, et al.
Publicado: (2022)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Elucidating the material basis and potential mechanisms of Ershiwuwei Lvxue Pill acting on rheumatoid arthritis by UPLC-Q-TOF/MS and network pharmacology
por: Liu, Chuan, et al.
Publicado: (2022)

Exploring potential mechanism of ciwujia tablets for insomnia by UPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation
por: Liu, Hongda, et al.
Publicado: (2022)

Potential mechanism of the Shunaoxin pill for preventing cognitive impairment in type 2 diabetes mellitus
por: Guo, Yuejie, et al.
Publicado: (2022)

The Integrated Study on the Chemical Profiling to Explore the Constituents and Mechanism of Traditional Chinese Medicine Preparation Huatuo Jiuxin Pills Based on UPLC-Q-TOF/MS(E) and Network Pharmacology
por: Zhu, Yulong, et al.
Publicado: (2022)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E)
por: Zhao, Xiangsheng, et al.
Publicado: (2018)

Based on UPLC-Q-TOF-MS/MS, Systematic Network Pharmacology, and Molecular Docking to Explore the Potential Mechanism of Fructus Aurantii for Major Depression Disorder
por: Xie, Yating, et al.
Publicado: (2021)

The Screening Research of NF-κB Inhibitors from Moutan Cortex Based on Bioactivity-Integrated UPLC-Q/TOF-MS
por: Lu, Yujie, et al.
Publicado: (2019)

Evaluation of the Effects of Processing Technique on Chemical Components in Raphani Semen by HPLC and UPLC-Q-TOF-MS
por: Gao, Sijia, et al.
Publicado: (2022)

Screening anti-fatigue components of American ginseng saponin by analyzing spectrum–effect relationship coupled with UPLC-Q-TOF-MS
por: Lin, Meiyu, et al.
Publicado: (2023)

Exploring the components and mechanisms of Shen-qi-wang-mo granule in the treatment of retinal vein occlusion by UPLC-Triple TOF MS/MS and network pharmacology
por: Zhao, Yi, et al.
Publicado: (2023)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
por: Xue, Ying, et al.
Publicado: (2018)

Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of Coreopsis tinctoria Nutt.
por: Liu, Jing, et al.
Publicado: (2022)

Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)
por: Bai, Yue, et al.
Publicado: (2019)

Identification of Antitumor Active Constituents in Polygonatum sibiricum Flower by UPLC-Q-TOF-MS(E) and Network Pharmacology
por: Huang, Zhuang-zhuang, et al.
Publicado: (2020)

Combination of UPLC–Q-TOF/MS and Network Pharmacology to Reveal the Mechanism of Qizhen Decoction in the Treatment of Colon Cancer
por: Kong, Xianbin, et al.
Publicado: (2021)

Integrated Phytochemical Analysis Based on UPLC-Q-TOF-MS/MS, Network Pharmacology, and Experiment Verification to Explore the Potential Mechanism of Platycodon grandiflorum for Chronic Bronchitis
por: Deng, Yaling, et al.
Publicado: (2020)

Combining UPLC/Q-TOF-MS/MS With Biological Evaluation for NF-κB Inhibitors in Uyghur Medicine Althaea rosea Flowers
por: Ma, Fang, et al.
Publicado: (2019)

Screening and Identification for Immunological Active Components from Andrographis Herba Using Macrophage Biospecific Extraction Coupled with UPLC/Q-TOF-MS
por: Wang, Yaqi, et al.
Publicado: (2018)

UPLC/Q-TOF MS Screening and Identification of Antibacterial Compounds in Forsythia suspensa (Thunb.) Vahl Leaves
por: Zhou, Mingyue, et al.
Publicado: (2022)

UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment
por: Duan, Xianchun, et al.
Publicado: (2020)

Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
por: Gong, Leilei, et al.
Publicado: (2018)

Metabolomics Study of Different Germplasm Resources for Three Polygonatum Species Using UPLC-Q-TOF-MS/MS
por: Wang, Shiqiang, et al.
Publicado: (2022)

The Effect of Temperature on Pressurised Hot Water Extraction of Pharmacologically Important Metabolites as Analysed by UPLC-qTOF-MS and PCA
por: Khoza, B. S., et al.
Publicado: (2014)

Unveiling the Pharmacological Mechanisms of Eleutheroside E Against Postmenopausal Osteoporosis Through UPLC-Q/TOF-MS-Based Metabolomics
por: Ma, Yong-Sheng, et al.
Publicado: (2020)

Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills
por: Liu, Jiani, et al.
Publicado: (2021)

Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH-UPLC-Q-TOF/MS Method
por: Wang, Gang, et al.
Publicado: (2015)

Rapid Classification and Identification of Chemical Components of Schisandra Chinensis by UPLC-Q-TOF/MS Combined with Data Post-Processing
por: Yang, Shenshen, et al.
Publicado: (2017)

Identification and differentiation of major components in three different “Sheng-ma” crude drug species by UPLC/Q-TOF-MS
por: Fan, Mengxue, et al.
Publicado: (2017)

Identification and quantitation of the actual active components in bamboo juice and its oral liquid by NMR and UPLC-Q-TOF-MS
por: Gao, Quan, et al.
Publicado: (2020)

Rapid Screening of Chemical Constituents in Rhizoma Anemarrhenae by UPLC-Q-TOF/MS Combined with Data Postprocessing Techniques
por: Shan, Lanlan, et al.
Publicado: (2017)

Identification of “Multiple Components-Multiple Targets-Multiple Pathways” Associated with Naoxintong Capsule in the Treatment of Heart Diseases Using UPLC/Q-TOF-MS and Network Pharmacology
por: Ma, Xianghui, et al.
Publicado: (2016)

Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS
por: Meng, Fanyu, et al.
Publicado: (2020)

Systematically characterize the substance basis of Jinzhen oral liquid and their pharmacological mechanism using UPLC-Q-TOF/MS combined with network pharmacology analysis
por: Guo, Jing-Yan, et al.
Publicado: (2019)

Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS
por: Han, Ya-Xin, et al.
Publicado: (2018)

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS
por: He, Xicheng, et al.
Publicado: (2016)

Comprehensive metabolomics study on the pathogenesis of anaplastic astrocytoma via UPLC-Q/TOF-MS
por: Du, Chao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_d0sidcofj7l62l63pqve0id1b8