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Compositional complementarity between genomic RNA and coat proteins in positive-sense single-stranded RNA viruses

During packaging in positive-sense single-stranded RNA (+ssRNA) viruses, coat proteins (CPs) interact directly with multiple regions in genomic RNA (gRNA), but the underlying physicochemical principles remain unclear. Here we analyze the high-resolution cryo-EM structure of bacteriophage MS2 and sho...

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Detalles Bibliográficos
Autores principales: Adlhart, Marlene, Poetsch, Florian, Hlevnjak, Mario, Hoogmoed, Megan, Polyansky, Anton A, Zagrovic, Bojan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023274/
https://www.ncbi.nlm.nih.gov/pubmed/35357492
http://dx.doi.org/10.1093/nar/gkac202