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Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor

Spatial genome organization is tightly controlled by several regulatory mechanisms and is essential for gene expression control. Nuclear receptors are ligand-activated transcription factors that modulate physiological and pathophysiological processes and are primary pharmacological targets. DNA bind...

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Detalles Bibliográficos
Autores principales: Warwick, Timothy, Schulz, Marcel H, Gilsbach, Ralf, Brandes, Ralf P, Seuter, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023275/
https://www.ncbi.nlm.nih.gov/pubmed/35325193
http://dx.doi.org/10.1093/nar/gkac178