Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome

Genomic DNA replication requires replisome assembly. We show here the molecular mechanism by which CMG (GAN–MCM–GINS)-like helicase cooperates with the family D DNA polymerase (PolD) in Thermococcus kodakarensis. The archaeal GINS contains two Gins51 subunits, the C-terminal domain of which (Gins51C...

Descripción completa

Detalles Bibliográficos
Autores principales: Oki, Keisuke, Nagata, Mariko, Yamagami, Takeshi, Numata, Tomoyuki, Ishino, Sonoko, Oyama, Takuji, Ishino, Yoshizumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023282/
https://www.ncbi.nlm.nih.gov/pubmed/34568951
http://dx.doi.org/10.1093/nar/gkab799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023282/
https://www.ncbi.nlm.nih.gov/pubmed/34568951
http://dx.doi.org/10.1093/nar/gkab799

Ejemplares similares