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Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome

Genomic DNA replication requires replisome assembly. We show here the molecular mechanism by which CMG (GAN–MCM–GINS)-like helicase cooperates with the family D DNA polymerase (PolD) in Thermococcus kodakarensis. The archaeal GINS contains two Gins51 subunits, the C-terminal domain of which (Gins51C...

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Detalles Bibliográficos
Autores principales:	Oki, Keisuke, Nagata, Mariko, Yamagami, Takeshi, Numata, Tomoyuki, Ishino, Sonoko, Oyama, Takuji, Ishino, Yoshizumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023282/ https://www.ncbi.nlm.nih.gov/pubmed/34568951 http://dx.doi.org/10.1093/nar/gkab799

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