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H3K56 deacetylation and H2A.Z deposition are required for aberrant heterochromatin spreading

Crucial mechanisms are required to restrict self-propagating heterochromatin spreading within defined boundaries and prevent euchromatic gene silencing. In the filamentous fungus Neurospora crassa, the JmjC domain protein DNA METHYLATION MODULATOR-1 (DMM-1) prevents aberrant spreading of heterochrom...

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Detalles Bibliográficos
Autores principales: Zhang, Chengcheng, Tian, Yuan, Song, Shuang, Zhang, Lu, Dang, Yunkun, He, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023284/
https://www.ncbi.nlm.nih.gov/pubmed/35333354
http://dx.doi.org/10.1093/nar/gkac196