Oxidative stress-CBP axis modulates MOB1 acetylation and activates the Hippo signaling pathway

Reactive oxygen species (ROS) are constantly produced in cells, an excess of which causes oxidative stress. ROS has been linked to regulation of the Hippo pathway; however, the underlying detailed mechanisms remain unclear. Here, we report that MOB1, a substrate of MST1/2 and co-activator of LATS1/2...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Jiaqi, Zhang, Lei, Li, Xueying, Xu, Weizhi, Yang, Siyuan, Song, Jiagui, Zhang, Wenhao, Zhan, Jun, Luo, Jianyuan, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023286/
https://www.ncbi.nlm.nih.gov/pubmed/35349706
http://dx.doi.org/10.1093/nar/gkac189

Ejemplares similares

Ejemplares similares