SWAN pathway-network identification of common aneuploidy-based oncogenic drivers

Haploinsufficiency drives Darwinian evolution. Siblings, while alike in many aspects, differ due to monoallelic differences inherited from each parent. In cancer, solid tumors exhibit aneuploid genetics resulting in hundreds to thousands of monoallelic gene-level copy-number alterations (CNAs) in ea...

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Detalles Bibliográficos
Autores principales: Bowers, Robert R, Jones, Christian M, Paz, Edwin A, Barrows, John K, Armeson, Kent E, Long, David T, Delaney, Joe R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023287/
https://www.ncbi.nlm.nih.gov/pubmed/35380699
http://dx.doi.org/10.1093/nar/gkac200

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