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NMR-derived secondary structure of the full-length Ox40 mRNA 3′UTR and its multivalent binding to the immunoregulatory RBP Roquin

Control of posttranscriptional mRNA decay is a crucial determinant of cell homeostasis and differentiation. mRNA lifetime is governed by cis-regulatory elements in their 3′ untranslated regions (UTR). Despite ongoing progress in the identification of cis elements we have little knowledge about the f...

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Detalles Bibliográficos
Autores principales:	Tants, Jan-Niklas, Becker, Lea Marie, McNicoll, François, Müller-McNicoll, Michaela, Schlundt, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023295/ https://www.ncbi.nlm.nih.gov/pubmed/35357505 http://dx.doi.org/10.1093/nar/gkac212

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