TREX1 degrades the 3′ end of the small DNA oligonucleotide products of nucleotide excision repair in human cells

The nucleotide excision repair (NER) machinery removes UV photoproducts from DNA in the form of small, excised damage-containing DNA oligonucleotides (sedDNAs) ∼30 nt in length. How cells process and degrade these byproducts of DNA repair is not known. Using a small scale RNA interference screen in...

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Detalles Bibliográficos
Autores principales: Kim, Seon Hee, Kim, Geun Hoe, Kemp, Michael G, Choi, Jun-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023299/
https://www.ncbi.nlm.nih.gov/pubmed/35357486
http://dx.doi.org/10.1093/nar/gkac214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023299/
https://www.ncbi.nlm.nih.gov/pubmed/35357486
http://dx.doi.org/10.1093/nar/gkac214

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