Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population

Although a subset of head and neck cancers (HNC) has been associated worldwide with mucosal high-risk human papillomaviruses (HPV), information on the prevalence of HPV-positive HNC in India is limited. In this study, we examined the prevalence of 21 subtypes of HPV in sub-sites of HNC (n = 175) in...

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Autores principales: Gholap, Devyani, Mhatre, Sharayu, Chaturvedi, Pankaj, Nair, Sudhir, Gheit, Tarik, Tommasino, Massimo, Dikshit, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023304/
https://www.ncbi.nlm.nih.gov/pubmed/35510141
http://dx.doi.org/10.3332/ecancer.2022.1358
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author Gholap, Devyani
Mhatre, Sharayu
Chaturvedi, Pankaj
Nair, Sudhir
Gheit, Tarik
Tommasino, Massimo
Dikshit, Rajesh
author_facet Gholap, Devyani
Mhatre, Sharayu
Chaturvedi, Pankaj
Nair, Sudhir
Gheit, Tarik
Tommasino, Massimo
Dikshit, Rajesh
author_sort Gholap, Devyani
collection PubMed
description Although a subset of head and neck cancers (HNC) has been associated worldwide with mucosal high-risk human papillomaviruses (HPV), information on the prevalence of HPV-positive HNC in India is limited. In this study, we examined the prevalence of 21 subtypes of HPV in sub-sites of HNC (n = 175) in the western region of India. Type-specific multiplex genotyping assay was conducted at the Centre for Cancer Epidemiology, Tata Memorial Centre, to determine the prevalence of HPV subtypes. The HPV prevalence was observed to be 28.43%, 41.67%, 38.89% and 15.79% in the oral cavity, oropharynx, hypopharynx and larynx tumour tissues, respectively. The HPV 16 genotype was most common in all HNC tumour tissues (30.29%), followed by HPV 58 (0.57%).
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spelling pubmed-90233042022-05-03 Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population Gholap, Devyani Mhatre, Sharayu Chaturvedi, Pankaj Nair, Sudhir Gheit, Tarik Tommasino, Massimo Dikshit, Rajesh Ecancermedicalscience Short Communication Although a subset of head and neck cancers (HNC) has been associated worldwide with mucosal high-risk human papillomaviruses (HPV), information on the prevalence of HPV-positive HNC in India is limited. In this study, we examined the prevalence of 21 subtypes of HPV in sub-sites of HNC (n = 175) in the western region of India. Type-specific multiplex genotyping assay was conducted at the Centre for Cancer Epidemiology, Tata Memorial Centre, to determine the prevalence of HPV subtypes. The HPV prevalence was observed to be 28.43%, 41.67%, 38.89% and 15.79% in the oral cavity, oropharynx, hypopharynx and larynx tumour tissues, respectively. The HPV 16 genotype was most common in all HNC tumour tissues (30.29%), followed by HPV 58 (0.57%). Cancer Intelligence 2022-02-18 /pmc/articles/PMC9023304/ /pubmed/35510141 http://dx.doi.org/10.3332/ecancer.2022.1358 Text en © the authors; licensee ecancermedicalscience. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Gholap, Devyani
Mhatre, Sharayu
Chaturvedi, Pankaj
Nair, Sudhir
Gheit, Tarik
Tommasino, Massimo
Dikshit, Rajesh
Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population
title Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population
title_full Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population
title_fullStr Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population
title_full_unstemmed Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population
title_short Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population
title_sort prevalence of human papillomavirus types in head and neck cancer sub-sites in the indian population
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023304/
https://www.ncbi.nlm.nih.gov/pubmed/35510141
http://dx.doi.org/10.3332/ecancer.2022.1358
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