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Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

The rapid spread of COVID-19 has caused a worldwide public health crisis. For prompt and effective development of antivirals for SARS-CoV-2, the pathogen of COVID-19, drug repurposing has been broadly conducted by targeting the main protease (M(Pro)), a key enzyme responsible for the replication of...

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Detalles Bibliográficos
Autores principales: Yang, Kai S., Alex Kuo, Syuan-Ting, Blankenship, Lauren R., Geng, Zhi Zachary, Li, Shuhua G., Russell, David H., Yan, Xin, Xu, Shiqing, Liu, Wenshe Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023366/
https://www.ncbi.nlm.nih.gov/pubmed/35815070
http://dx.doi.org/10.1016/j.crchbi.2022.100025