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Breast cancer hypoxia in relation to prognosis and benefit from radiotherapy after breast-conserving surgery in a large, randomised trial with long-term follow-up

BACKGROUND: Breast-conserving surgery followed by radiotherapy is part of standard treatment for early-stage breast cancer. Hypoxia is common in cancer and may affect the benefit of radiotherapy. Cells adapt to hypoxic stress largely via the transcriptional activity of hypoxia-inducible factor (HIF)...

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Detalles Bibliográficos
Autores principales:	Tutzauer, Julia, Sjöström, Martin, Holmberg, Erik, Karlsson, Per, Killander, Fredrika, Leeb-Lundberg, L. M. Fredrik, Malmström, Per, Niméus, Emma, Fernö, Mårten, Jögi, Annika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023448/ https://www.ncbi.nlm.nih.gov/pubmed/35140341 http://dx.doi.org/10.1038/s41416-021-01630-4

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