Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation

Large-scale target cell isolation from patient blood preparations is one of the critical operations during drug product manufacturing for personalized cell therapy in immuno-oncology. Use of high-affinity murine antibody coated magnetic nanoparticles that remain on isolated cells is the current stan...

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Detalles Bibliográficos
Autores principales: Radisch, Sabine, Poltorak, Mateusz P., Wagner, Michaela, Cletiu, Vlad, Radisch, Christian, Treise, Irina, Pann, Steffi, Weigt, Alexis, Artner, Sophie, Dreher, Stefan, Fechner, Fabian, Borjan, Bojana, Fraessle, Simon P., Effenberger, Manuel, Benke, Eileen, Navratil, Gottfried, Hentschel, Norbert, Busch, Dirk H., Schmidt, Thomas, Stemberger, Christian, Germeroth, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023455/
https://www.ncbi.nlm.nih.gov/pubmed/35449227
http://dx.doi.org/10.1038/s41598-022-10320-x

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