Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Defective CFTR leads to accumulation of dehydrated viscous mucus within the small intestine, luminal acidification and altered intestinal motility, resulting in blockage. These changes...

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Detalles Bibliográficos
Autores principales: Kelly, Jennifer, Al-Rammahi, Miran, Daly, Kristian, Flanagan, Paul K., Urs, Arun, Cohen, Marta C., di Stefano, Gabriella, Bijvelds, Marcel J. C., Sheppard, David N., de Jonge, Hugo R., Seidler, Ursula E., Shirazi-Beechey, Soraya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023491/
https://www.ncbi.nlm.nih.gov/pubmed/35449374
http://dx.doi.org/10.1038/s41598-022-10328-3

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