Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles

Repurposing FDA-approved drugs is an efficient and cost-effective approach in the development of therapeutics for a broad range of diseases. However, prediction of function can be challenging, especially in the brain. We screened a small-molecule library with FDA-approved drugs for effects on behavi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tucker Edmister, Sara, Del Rosario Hernández, Thaís, Ibrahim, Rahma, Brown, Cameron A., Gore, Sayali V., Kakodkar, Rohit, Kreiling, Jill A., Creton, Robbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023506/
https://www.ncbi.nlm.nih.gov/pubmed/35449173
http://dx.doi.org/10.1038/s41598-022-10133-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023506/
https://www.ncbi.nlm.nih.gov/pubmed/35449173
http://dx.doi.org/10.1038/s41598-022-10133-y

Ejemplares similares