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Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles
Repurposing FDA-approved drugs is an efficient and cost-effective approach in the development of therapeutics for a broad range of diseases. However, prediction of function can be challenging, especially in the brain. We screened a small-molecule library with FDA-approved drugs for effects on behavi...
Autores principales: | Tucker Edmister, Sara, Del Rosario Hernández, Thaís, Ibrahim, Rahma, Brown, Cameron A., Gore, Sayali V., Kakodkar, Rohit, Kreiling, Jill A., Creton, Robbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023506/ https://www.ncbi.nlm.nih.gov/pubmed/35449173 http://dx.doi.org/10.1038/s41598-022-10133-y |
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