Cargando…

Increased biomarkers of cardiovascular risk in HIV-1 viremic controllers and low persistent inflammation in elite controllers and art-suppressed individuals

HIV controllers (HICs) are models of HIV functional cure, although some studies have shown persistent inflammation and increased rates of atherosclerosis in HICs. Since immune activation/inflammation contributes to the pathogenesis of cardiovascular diseases (CVD), we evaluated clinical data and inf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Caetano, Diogo Gama, Ribeiro-Alves, Marcelo, Hottz, Eugênio Damaceno, Vilela, Larissa Melo, Cardoso, Sandra Wagner, Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea Gonçalves, Morgado, Mariza Gonçalves, Bozza, Patrícia Torres, Guimarães, Monick Lindenmeyer, Côrtes, Fernanda Heloise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023525/ https://www.ncbi.nlm.nih.gov/pubmed/35449171 http://dx.doi.org/10.1038/s41598-022-10330-9

Ejemplares similares

Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control
por: Caetano, Diogo Gama, et al.
Publicado: (2018)

A case report of HIV-1 superinfection in an HIV controller leading to loss of viremia control: a retrospective of 10 years of follow-up
por: Caetano, Diogo Gama, et al.
Publicado: (2019)

HIV-1 elite controllers present a high frequency of activated regulatory T and Th17 cells
por: Caetano, Diogo G., et al.
Publicado: (2020)

Ongoing HIV-1 evolution and reservoir reseeding in two elite controllers with genetically diverse peripheral proviral quasispecies
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2023)

Plasmatic Levels of IL-18, IP-10, and Activated CD8(+) T Cells Are Potential Biomarkers to Identify HIV-1 Elite Controllers With a True Functional Cure Profile
por: Côrtes, Fernanda H., et al.
Publicado: (2018)

Reduction of inflammation and T cell activation after 6 months of cART initiation during acute, but not in early chronic HIV-1 infection
por: de Paula, Hury Hellen Souza, et al.
Publicado: (2018)

Reduction of HIV-1 Reservoir Size and Diversity After 1 Year of cART Among Brazilian Individuals Starting Treatment During Early Stages of Acute Infection
por: Leite, Thaysse Ferreira, et al.
Publicado: (2019)

Proviral Quasispecies Diversity Is Not Associated With Virologic Breakthrough or CD4(+) T Cell Loss in HIV-1 Elite Controllers
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2019)

Association of Single Nucleotide Polymorphisms in the Lens Epithelium-Derived Growth Factor (LEDGF/p75) with HIV-1 Infection Outcomes in Brazilian HIV-1+ Individuals
por: Passaes, Caroline Pereira Bittencourt, et al.
Publicado: (2014)

Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2017)

Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil
por: Marques, Bianca Cristina Leires, et al.
Publicado: (2018)

Comparative HIV-1 Proviral Dynamics in Two Individuals That Maintained Viral Replication Control with or without Antiretroviral Therapy following Superinfection
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2022)

Elite and viremic HIV-1 controllers in West Africa
por: N’takpé, Jean Baptiste, et al.
Publicado: (2022)

Cross-Neutralizing Antibodies in HIV-1 Individuals Infected by Subtypes B, F1, C or the B/Bbr Variant in Relation to the Genetics and Biochemical Characteristics of the env Gene
por: de Almeida, Dalziza Victalina, et al.
Publicado: (2016)

Mechanisms of Virologic Control and Clinical Characteristics of HIV+ Elite/Viremic Controllers
por: Gonzalo-Gil, Elena, et al.
Publicado: (2017)

Identification of a new circulating recombinant form of human immunodeficiency virus type 1, CRF124_cpx involving subtypes A, G, H, and CRF27_cpx in Angola
por: Da Silva, Rayana Katylin Mendes, et al.
Publicado: (2022)

Assessing the HIV-1 Epidemic in Brazilian Drug Users: A Molecular Epidemiology Approach
por: Guimarães, Monick Lindenmeyer, et al.
Publicado: (2015)

Transplantation of HCV Viremic Livers into HCV Viremic Recipients Followed by Direct-acting Antiviral Therapy
por: Kapila, Nikhil, et al.
Publicado: (2019)

Genetic Characterization of a New HIV-1 Sub-Subtype A in Cabo Verde, Denominated A8
por: Mendes Da Silva, Rayana Katylin, et al.
Publicado: (2021)

Acute to post-acute COVID-19 thromboinflammation persistence: Mechanisms and potential consequences
por: Martins-Gonçalves, Remy, et al.
Publicado: (2023)

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2020)

Brief Report: Identification of Elite and Viremic Controllers From a Large Urban HIV Ambulatory Center in Kampala, Uganda
por: Kayongo, Alex, et al.
Publicado: (2018)

Prevalence, estimated HIV-1 incidence and viral diversity among people seeking voluntary counseling and testing services in Rio de Janeiro, Brazil
por: de Castro, Carlos A Velasco, et al.
Publicado: (2010)

Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review
por: Coelho, Lara, et al.
Publicado: (2013)

Differential MicroRNA Expression Profile between Stimulated PBMCs from HIV-1 Infected Elite Controllers and Viremic Progressors
por: Egaña-Gorroño, Lander, et al.
Publicado: (2014)

HIV-1 Diversity and Drug Resistance Mutations among People Seeking HIV Diagnosis in Voluntary Counseling and Testing Sites in Rio de Janeiro, Brazil
por: Velasco-de-Castro, Carlos A., et al.
Publicado: (2014)

Awareness of Prevention Strategies and Willingness to Use Preexposure Prophylaxis in Brazilian Men Who Have Sex With Men Using Apps for Sexual Encounters: Online Cross-Sectional Study
por: Torres, Thiago Silva, et al.
Publicado: (2018)

Platelet‐leukocyte interactions in COVID‐19: Contributions to hypercoagulability, inflammation, and disease severity
por: Hottz, Eugenio D., et al.
Publicado: (2022)

Robust HIV-specific CD4(+) and CD8(+) T-cell responses distinguish elite control in adolescents living with HIV from viremic nonprogressors
por: Vieira, Vinicius A., et al.
Publicado: (2022)

Transmitted drug resistance in patients with acute/recent HIV infection in Brazil
por: Ferreira, Ana Cristina G., et al.
Publicado: (2017)

Platelets in Immune Response to Virus and Immunopathology of Viral Infections
por: Hottz, Eugenio D., et al.
Publicado: (2018)

Telemedicine as a tool for PrEP delivery during the COVID-19 pandemic in a large HIV prevention service in Rio de Janeiro-Brazil
por: Hoagland, Brenda, et al.
Publicado: (2020)

High acceptability of PrEP teleconsultation and HIV self-testing among PrEP users during the COVID-19 pandemic in Brazil
por: Hoagland, Brenda, et al.
Publicado: (2020)

Unprotected sex among men who have sex with men living with HIV in Brazil: a cross-sectional study in Rio de Janeiro
por: Cunha, Cynthia Braga, et al.
Publicado: (2014)

Evaluation of Anti-PF4 Positivity and Platelet Activation after COVID-19 Vaccination with Ad26.COV2.S in Brazil
por: Bokel, Joanna, et al.
Publicado: (2022)

Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil
por: Neira-Goulart, Milena, et al.
Publicado: (2023)

Sustained Viremic Control in HIV-Infected Patient: Case Report from Nepal
por: Khadka, Sundar, et al.
Publicado: (2018)

A Peer-Led Digital Intervention to Reduce HIV Prevention and Care Disparities Among Young Brazilian Transgender Women (The BeT Study): Protocol for an Intervention Study
por: Jalil, Emilia Moreira, et al.
Publicado: (2023)

HIV-1 Diversity and Drug Resistance in Treatment-Naïve Children and Adolescents from Rio de Janeiro, Brazil
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2022)

Inflammasome in Platelets: Allying Coagulation and Inflammation in Infectious and Sterile Diseases?
por: Hottz, Eugenio D., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_a4hf3uvl532f7g64q2i9sfoi6v