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Regorafenib inhibits epithelial-mesenchymal transition and suppresses cholangiocarcinoma metastasis via YAP1-AREG axis

Cholangiocarcinoma (CCA) is a subtype of bile duct cancer usually diagnosed late with a low survival rate and no satisfactorily systemic treatment. Recently, regorafenib has been accepted as a second-line treatment for CCA patients. In this study, we investigated the potential signal transduction pa...

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Detalles Bibliográficos
Autores principales:	Chang, Yu-Chan, Li, Chien-Hsiu, Chan, Ming-Hsien, Chen, Ming-Huang, Yeh, Chun-Nan, Hsiao, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023529/ https://www.ncbi.nlm.nih.gov/pubmed/35449153 http://dx.doi.org/10.1038/s41419-022-04816-7

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