A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells

Despite the widespread use of human pluripotent stem cells (hPSCs), there is no general consensus with respect to monitoring the integrity of nuclear and mitochondrial genome of hPSCs. We argue that clear guidelines should be in place, and we have identified frequently asked questions that can be us...

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Detalles Bibliográficos
Autores principales: Rossi, Andrea, Lickfett, Selene, Martins, Soraia, Prigione, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023764/
https://www.ncbi.nlm.nih.gov/pubmed/35245442
http://dx.doi.org/10.1016/j.stemcr.2022.01.019
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author Rossi, Andrea
Lickfett, Selene
Martins, Soraia
Prigione, Alessandro
author_facet Rossi, Andrea
Lickfett, Selene
Martins, Soraia
Prigione, Alessandro
author_sort Rossi, Andrea
collection PubMed
description Despite the widespread use of human pluripotent stem cells (hPSCs), there is no general consensus with respect to monitoring the integrity of nuclear and mitochondrial genome of hPSCs. We argue that clear guidelines should be in place, and we have identified frequently asked questions that can be used to develop a practical guide for hPSCs users.
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spelling pubmed-90237642022-04-23 A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells Rossi, Andrea Lickfett, Selene Martins, Soraia Prigione, Alessandro Stem Cell Reports Forum Despite the widespread use of human pluripotent stem cells (hPSCs), there is no general consensus with respect to monitoring the integrity of nuclear and mitochondrial genome of hPSCs. We argue that clear guidelines should be in place, and we have identified frequently asked questions that can be used to develop a practical guide for hPSCs users. Elsevier 2022-03-03 /pmc/articles/PMC9023764/ /pubmed/35245442 http://dx.doi.org/10.1016/j.stemcr.2022.01.019 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Forum
Rossi, Andrea
Lickfett, Selene
Martins, Soraia
Prigione, Alessandro
A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
title A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
title_full A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
title_fullStr A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
title_full_unstemmed A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
title_short A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
title_sort call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
topic Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023764/
https://www.ncbi.nlm.nih.gov/pubmed/35245442
http://dx.doi.org/10.1016/j.stemcr.2022.01.019
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