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Is hypoimmunogenic stem cell therapy safe in times of pandemics?

The manipulation of human leukocyte antigens (HLAs) and immune modulatory factors in “universal” human pluripotent stem cells (PSCs) holds promise for immunological tolerance without HLA matching. This paradigm raises concerns should "universal" grafts become virally infected. Furthermore,...

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Detalles Bibliográficos
Autores principales: Matheus, Friederike, Raveh, Tal, Oro, Anthony E., Wernig, Marius, Drukker, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023772/
https://www.ncbi.nlm.nih.gov/pubmed/35334219
http://dx.doi.org/10.1016/j.stemcr.2022.02.014