Antioxidant and lipid supplementation improve the development of photoreceptor outer segments in pluripotent stem cell-derived retinal organoids

The generation of retinal organoids from human pluripotent stem cells (hPSC) is now a well-established process that in part recapitulates retinal development. However, hPSC-derived photoreceptors that exhibit well-organized outer segment structures have yet to be observed. To facilitate improved inh...

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Detalles Bibliográficos
Autores principales: West, Emma L., Majumder, Paromita, Naeem, Arifa, Fernando, Milan, O'Hara-Wright, Michelle, Lanning, Emily, Kloc, Magdalena, Ribeiro, Joana, Ovando-Roche, Patrick, Shum, Ian O., Jumbu, Neeraj, Sampson, Robert, Hayes, Matt, Bainbridge, James W.B., Georgiadis, Anastasios, Smith, Alexander J., Gonzalez-Cordero, Anai, Ali, Robin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023802/
https://www.ncbi.nlm.nih.gov/pubmed/35334217
http://dx.doi.org/10.1016/j.stemcr.2022.02.019

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