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Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro
The spinal cord emerges from a niche of neuromesodermal progenitors (NMPs) formed and maintained by WNT/fibroblast growth factor (FGF) signals at the posterior end of the embryo. NMPs can be generated from human pluripotent stem cells and hold promise for spinal cord replacement therapies. However,...
Autores principales: | Cooper, Fay, Gentsch, George E., Mitter, Richard, Bouissou, Camille, Healy, Lyn E., Rodriguez, Ana Hernandez, Smith, James C., Bernardo, Andreia S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023813/ https://www.ncbi.nlm.nih.gov/pubmed/35334218 http://dx.doi.org/10.1016/j.stemcr.2022.02.018 |
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