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Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro

The spinal cord emerges from a niche of neuromesodermal progenitors (NMPs) formed and maintained by WNT/fibroblast growth factor (FGF) signals at the posterior end of the embryo. NMPs can be generated from human pluripotent stem cells and hold promise for spinal cord replacement therapies. However,...

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Detalles Bibliográficos
Autores principales: Cooper, Fay, Gentsch, George E., Mitter, Richard, Bouissou, Camille, Healy, Lyn E., Rodriguez, Ana Hernandez, Smith, James C., Bernardo, Andreia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023813/
https://www.ncbi.nlm.nih.gov/pubmed/35334218
http://dx.doi.org/10.1016/j.stemcr.2022.02.018

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