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Not-so-minimal for minimally invasive surgery
Sub-macular hemorrhage poses a potential threat to vision if left untreated. The preferred surgical technique to clear sub-macular hemorrhage includes vitrectomy followed by retinotomy using a 41G needle with subsequent injection of recombinant tissue plasminogen activator (r-tPA) followed by air/SF...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023919/ https://www.ncbi.nlm.nih.gov/pubmed/35086260 http://dx.doi.org/10.4103/ijo.IJO_1726_21 |
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author | Ramesh, Arpitha Ramanjulu, Rajesh Shanmugam, Mahesh P Chaitanya, Vivek |
author_facet | Ramesh, Arpitha Ramanjulu, Rajesh Shanmugam, Mahesh P Chaitanya, Vivek |
author_sort | Ramesh, Arpitha |
collection | PubMed |
description | Sub-macular hemorrhage poses a potential threat to vision if left untreated. The preferred surgical technique to clear sub-macular hemorrhage includes vitrectomy followed by retinotomy using a 41G needle with subsequent injection of recombinant tissue plasminogen activator (r-tPA) followed by air/SF6 injection into the sub-retinal space. A malleable nature, increased resistance, and the cost of the 41G needle limit its use. We evaluated the safety and efficacy of a 26G needle for retinotomy as a supplement for the 41G needle in a series of six subjects with sub-macular hemorrhage. A slight modification in the procedure was done by injecting air into the sub-retinal space prior to the r-tPA injection. We found that our technique of using the 26G needle for retinotomy is safe and effective due to its stable nature and self-sealing properties. An air injection prior to r-tPA allows for increased bioavailability of the drug by preventing efflux due to its tamponading effect. |
format | Online Article Text |
id | pubmed-9023919 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-90239192022-04-23 Not-so-minimal for minimally invasive surgery Ramesh, Arpitha Ramanjulu, Rajesh Shanmugam, Mahesh P Chaitanya, Vivek Indian J Ophthalmol Surgical Technique Sub-macular hemorrhage poses a potential threat to vision if left untreated. The preferred surgical technique to clear sub-macular hemorrhage includes vitrectomy followed by retinotomy using a 41G needle with subsequent injection of recombinant tissue plasminogen activator (r-tPA) followed by air/SF6 injection into the sub-retinal space. A malleable nature, increased resistance, and the cost of the 41G needle limit its use. We evaluated the safety and efficacy of a 26G needle for retinotomy as a supplement for the 41G needle in a series of six subjects with sub-macular hemorrhage. A slight modification in the procedure was done by injecting air into the sub-retinal space prior to the r-tPA injection. We found that our technique of using the 26G needle for retinotomy is safe and effective due to its stable nature and self-sealing properties. An air injection prior to r-tPA allows for increased bioavailability of the drug by preventing efflux due to its tamponading effect. Wolters Kluwer - Medknow 2022-02 2022-01-27 /pmc/articles/PMC9023919/ /pubmed/35086260 http://dx.doi.org/10.4103/ijo.IJO_1726_21 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Surgical Technique Ramesh, Arpitha Ramanjulu, Rajesh Shanmugam, Mahesh P Chaitanya, Vivek Not-so-minimal for minimally invasive surgery |
title | Not-so-minimal for minimally invasive surgery |
title_full | Not-so-minimal for minimally invasive surgery |
title_fullStr | Not-so-minimal for minimally invasive surgery |
title_full_unstemmed | Not-so-minimal for minimally invasive surgery |
title_short | Not-so-minimal for minimally invasive surgery |
title_sort | not-so-minimal for minimally invasive surgery |
topic | Surgical Technique |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023919/ https://www.ncbi.nlm.nih.gov/pubmed/35086260 http://dx.doi.org/10.4103/ijo.IJO_1726_21 |
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