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Not-so-minimal for minimally invasive surgery

Sub-macular hemorrhage poses a potential threat to vision if left untreated. The preferred surgical technique to clear sub-macular hemorrhage includes vitrectomy followed by retinotomy using a 41G needle with subsequent injection of recombinant tissue plasminogen activator (r-tPA) followed by air/SF...

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Autores principales: Ramesh, Arpitha, Ramanjulu, Rajesh, Shanmugam, Mahesh P, Chaitanya, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023919/
https://www.ncbi.nlm.nih.gov/pubmed/35086260
http://dx.doi.org/10.4103/ijo.IJO_1726_21
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author Ramesh, Arpitha
Ramanjulu, Rajesh
Shanmugam, Mahesh P
Chaitanya, Vivek
author_facet Ramesh, Arpitha
Ramanjulu, Rajesh
Shanmugam, Mahesh P
Chaitanya, Vivek
author_sort Ramesh, Arpitha
collection PubMed
description Sub-macular hemorrhage poses a potential threat to vision if left untreated. The preferred surgical technique to clear sub-macular hemorrhage includes vitrectomy followed by retinotomy using a 41G needle with subsequent injection of recombinant tissue plasminogen activator (r-tPA) followed by air/SF6 injection into the sub-retinal space. A malleable nature, increased resistance, and the cost of the 41G needle limit its use. We evaluated the safety and efficacy of a 26G needle for retinotomy as a supplement for the 41G needle in a series of six subjects with sub-macular hemorrhage. A slight modification in the procedure was done by injecting air into the sub-retinal space prior to the r-tPA injection. We found that our technique of using the 26G needle for retinotomy is safe and effective due to its stable nature and self-sealing properties. An air injection prior to r-tPA allows for increased bioavailability of the drug by preventing efflux due to its tamponading effect.
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spelling pubmed-90239192022-04-23 Not-so-minimal for minimally invasive surgery Ramesh, Arpitha Ramanjulu, Rajesh Shanmugam, Mahesh P Chaitanya, Vivek Indian J Ophthalmol Surgical Technique Sub-macular hemorrhage poses a potential threat to vision if left untreated. The preferred surgical technique to clear sub-macular hemorrhage includes vitrectomy followed by retinotomy using a 41G needle with subsequent injection of recombinant tissue plasminogen activator (r-tPA) followed by air/SF6 injection into the sub-retinal space. A malleable nature, increased resistance, and the cost of the 41G needle limit its use. We evaluated the safety and efficacy of a 26G needle for retinotomy as a supplement for the 41G needle in a series of six subjects with sub-macular hemorrhage. A slight modification in the procedure was done by injecting air into the sub-retinal space prior to the r-tPA injection. We found that our technique of using the 26G needle for retinotomy is safe and effective due to its stable nature and self-sealing properties. An air injection prior to r-tPA allows for increased bioavailability of the drug by preventing efflux due to its tamponading effect. Wolters Kluwer - Medknow 2022-02 2022-01-27 /pmc/articles/PMC9023919/ /pubmed/35086260 http://dx.doi.org/10.4103/ijo.IJO_1726_21 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Surgical Technique
Ramesh, Arpitha
Ramanjulu, Rajesh
Shanmugam, Mahesh P
Chaitanya, Vivek
Not-so-minimal for minimally invasive surgery
title Not-so-minimal for minimally invasive surgery
title_full Not-so-minimal for minimally invasive surgery
title_fullStr Not-so-minimal for minimally invasive surgery
title_full_unstemmed Not-so-minimal for minimally invasive surgery
title_short Not-so-minimal for minimally invasive surgery
title_sort not-so-minimal for minimally invasive surgery
topic Surgical Technique
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023919/
https://www.ncbi.nlm.nih.gov/pubmed/35086260
http://dx.doi.org/10.4103/ijo.IJO_1726_21
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