Cargando…

Serological Phenotyping Analysis Uncovers a Unique Metabolomic Pattern Associated With Early Onset of Type 2 Diabetes Mellitus

Background: Type 2 diabetes mellitus (T2DM) is a multifaceted disorder affecting epidemic proportion at global scope. Defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond effectively to insulin are the underlying biology of T2DM. However, circul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Linmin, Huang, Qianyang, Li, Xiao, Jin, Bo, Ding, Yun, Chou, C. James, Su, Kuo-Jung, Zhang, Yani, Chen, Xingguo, Hwa, Kuo Yuan, Thyparambil, Sheeno, Liao, Weili, Han, Zhi, Mortensen, Richard, Jin, Yi, Li, Zhen, Schilling, James, Sylvester, Karl G., Sun, Xuguo, Ling, Xuefeng B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024215/ https://www.ncbi.nlm.nih.gov/pubmed/35463946 http://dx.doi.org/10.3389/fmolb.2022.841209

Ejemplares similares

Altered expression of the L-arginine/nitric oxide pathway in ovarian cancer: metabolic biomarkers and biological implications
por: Chen, Linfeng, et al.
Publicado: (2023)

High-throughput quantitation of amino acids and acylcarnitine in cerebrospinal fluid: identification of PCNSL biomarkers and potential metabolic messengers
por: Ma, Jingjing, et al.
Publicado: (2023)

Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation
por: Huang, Qianyang, et al.
Publicado: (2021)

Evaluation and Comparison of Serological Methods for COVID-19 Diagnosis
por: Gong, Fanwu, et al.
Publicado: (2021)

Metabolism-Related Signature Analysis Uncovers the Prognostic and Immunotherapeutic Characteristics of Renal Cell Carcinoma
por: Zhang, Jianye, et al.
Publicado: (2022)

Why Selenocysteine Is Unique?
por: Serrão, Vitor Hugo Balasco, et al.
Publicado: (2020)

Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells
por: Sun, Lingtong, et al.
Publicado: (2022)

Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans
por: Frumkin, Anna, et al.
Publicado: (2014)

Functional metagenomics uncovers nitrile-hydrolysing enzymes in a coal metagenome
por: Achudhan, Arunmozhi Bharathi, et al.
Publicado: (2023)

Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma
por: Liu, Fei, et al.
Publicado: (2022)

Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness
por: Wang, Yue, et al.
Publicado: (2016)

RNA sequencing and lipidomics uncovers novel pathomechanisms in recessive X-linked ichthyosis
por: McGeoghan, Farrell, et al.
Publicado: (2023)

Protein adsorption by nanomechanical mass spectrometry: Beyond the real-time molecular weighting
por: Stachiv, Ivo, et al.
Publicado: (2023)

Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease Progression
por: Liu, Wenzhou, et al.
Publicado: (2022)

CYP19A1 (aromatase) dominates female gonadal differentiation in chicken (Gallus gallus) embryos sexual differentiation
por: Jin, Kai, et al.
Publicado: (2020)

Standing of nucleic acid testing strategies in veterinary diagnosis laboratories to uncover Mycobacterium tuberculosis complex members
por: Costa, Pedro, et al.
Publicado: (2014)

Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression
por: Wu, Min, et al.
Publicado: (2023)

Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum
por: Vydyam, Pratap, et al.
Publicado: (2023)

Targeting extracellular Hsp90: A unique frontier against cancer
por: Sager, Rebecca A., et al.
Publicado: (2022)

Uncovering the Mechanism of Drug Resistance Caused by the T790M Mutation in EGFR Kinase From Absolute Binding Free Energy Calculations
por: Zhou, Huaxin, et al.
Publicado: (2022)

Theory Meets Experiment: Metal Ion Effects in HCV Genomic RNA Kissing Complex Formation
por: Sun, Li-Zhen, et al.
Publicado: (2017)

Untargeted metabolomics screening reveals unique secondary metabolite production from Alternaria section Alternaria
por: Witte, Thomas E., et al.
Publicado: (2022)

Comparative Transcriptomics Uncover the Uniqueness of Oocyte Development in the Donkey
por: Zhang, Fa-Li, et al.
Publicado: (2022)

Transcriptional Network Analysis Reveals the Role of miR-223-5p During Diabetic Corneal Epithelial Regeneration
por: Zhang, Yuan, et al.
Publicado: (2021)

CircRNAs as Novel Biomarkers and Therapeutic Targets in Renal Cell Carcinoma
por: Zhou, Yuxia, et al.
Publicado: (2022)

SYDE1 Acts as an Oncogene in Glioma and has Diagnostic and Prognostic Values
por: Han, Zhenyuan, et al.
Publicado: (2021)

Uncovering the immune microenvironment and molecular subtypes of hepatitis B-related liver cirrhosis and developing stable a diagnostic differential model by machine learning and artificial neural networks
por: Zhang, Shengke, et al.
Publicado: (2023)

Development of an Immunogenomic Landscape-Based Prognostic Index of Head and Neck Squamous Cell Carcinoma
por: Long, Jinhua, et al.
Publicado: (2020)

Six-Month Outcomes of Post-ARDS Pulmonary Fibrosis in Patients With H1N1 Pneumonia
por: Gao, Jing, et al.
Publicado: (2021)

Identification of Prognostic Biomarkers in Patients With Malignant Rhabdoid Tumor of the Kidney Based on mTORC1 Signaling Pathway-Related Genes
por: Zhanghuang, Chenghao, et al.
Publicado: (2022)

Unique small RNA signatures uncovered in the tammar wallaby genome
por: Lindsay, James, et al.
Publicado: (2012)

Advances and Insights of APC-Asef Inhibitors for Metastatic Colorectal Cancer Therapy
por: Yang, Xiuyan, et al.
Publicado: (2021)

Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation
por: Yang, Zhen, et al.
Publicado: (2022)

Computational study on the binding of Mango-II RNA aptamer and fluorogen using the polarizable force field AMOEBA
por: Yang, Xudong, et al.
Publicado: (2022)

Degrees of Shortage and Uncovered Ratios for Long-Term Care in Taiwan’s Regions: Evidence from Dynamic DEA
por: Wu, Kuo-Feng, et al.
Publicado: (2021)

Clinical Application Value of Circulating Cell-free DNA in Hepatocellular Carcinoma
por: Zhang, Yuyuan, et al.
Publicado: (2021)

RNA Splicing: A Versatile Regulatory Mechanism in Pediatric Liver Diseases
por: Zhou, Jian-Li, et al.
Publicado: (2021)

Identification of Diagnostic Markers Correlated With HIV(+) Immune Non-response Based on Bioinformatics Analysis
por: Bai, Ruojing, et al.
Publicado: (2021)

Ischemic Postconditioning-Mediated DJ-1 Activation Mitigate Intestinal Mucosa Injury Induced by Myocardial Ischemia Reperfusion in Rats Through Keap1/Nrf2 Pathway
por: Chen, Rong, et al.
Publicado: (2021)

Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway
por: Pan, Cunyao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_72lj7f3e1dn0vmkgnsbov93gqj