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Bruceine H Mediates EGFR-TKI Drug Persistence in NSCLC by Notch3-Dependent β-Catenin Activating FOXO3a Signaling

Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) protein serve as a critical pillar in the treatment of non-small cell lung cancer (NSCLC), but resistance is universal. Identifying the potential key factors of drug resistance to EGFR-TKIs is essential to treat pati...

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Detalles Bibliográficos
Autores principales:	Wu, Jiahui, He, Xiao, Xiong, Ziwei, Shi, Lingyu, Chen, Daofeng, Feng, Yulin, Wen, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024338/ https://www.ncbi.nlm.nih.gov/pubmed/35463301 http://dx.doi.org/10.3389/fonc.2022.855603

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