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Integrating whole genome sequencing, methylation, gene expression, topological associated domain information in regulatory mutation prediction: A study of follicular lymphoma

A major challenge in human genetics is of the analysis of the interplay between genetic and epigenetic factors in a multifactorial disease like cancer. Here, a novel methodology is proposed to investigate genome-wide regulatory mechanisms in cancer, as studied with the example of follicular Lymphoma...

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Detalles Bibliográficos
Autores principales: Farooq, Amna, Trøen, Gunhild, Delabie, Jan, Wang, Junbai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024376/
https://www.ncbi.nlm.nih.gov/pubmed/35495111
http://dx.doi.org/10.1016/j.csbj.2022.03.023

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