Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment

IMPORTANCE: The diagnostic evaluation for Alzheimer disease may be improved by a blood-based diagnostic test identifying presence of brain amyloid plaque pathology. OBJECTIVE: To determine the clinical performance associated with a diagnostic algorithm incorporating plasma amyloid-β (Aβ) 42:40 ratio...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Kirmess, Kristopher M., Meyer, Matthew R., Rabinovici, Gil D., Gatsonis, Constantine, Siegel, Barry A., Whitmer, Rachel A., Apgar, Charles, Hanna, Lucy, Kanekiyo, Michio, Kaplow, June, Koyama, Akihiko, Verbel, David, Holubasch, Mary S., Knapik, Stephanie S., Connor, Jason, Contois, John H., Jackson, Erin N., Harpstrite, Scott E., Bateman, Randall J., Holtzman, David M., Verghese, Philip B., Fogelman, Ilana, Braunstein, Joel B., Yarasheski, Kevin E., West, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024390/
https://www.ncbi.nlm.nih.gov/pubmed/35446396
http://dx.doi.org/10.1001/jamanetworkopen.2022.8392

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