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The Secretome of Preconditioned Mesenchymal Stem Cells Drives Polarization and Reprogramming of M2a Macrophages toward an IL-10-Producing Phenotype
The preconditioning of mesenchymal stem cells (MSCs) has been recognized as an attractive tool to improve their regenerative and immunomodulatory capacities based on their paracrine effects. In this study, we examined the potential of an MSC-conditioned medium (MSC-CM) to alter the phenotype of muri...
Autores principales: | Holthaus, Michelle, Santhakumar, Nivethiha, Wahlers, Thorsten, Paunel-Görgülü, Adnana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024470/ https://www.ncbi.nlm.nih.gov/pubmed/35456922 http://dx.doi.org/10.3390/ijms23084104 |
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