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Add Sugar to Chitosan: Mucoadhesion and In Vitro Intestinal Permeability of Mannosylated Chitosan Nanocarriers

Crosslinked chitosan nanocarriers (140–160 nm) entrapping coumarin-6 (λ(ex/em) = 455/508 nm) with or without surface mannosylation were synthesized and assessed for cytotoxicity, adherence and cellular uptake in Caco-2 cells, flux across Caco-2 monolayers, and mucoadhesion to porcine mucin. Mannosyl...

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Detalles Bibliográficos
Autores principales:	Ejaz, Sadaf, Hogg, Bridget, Hristov, Delyan R., Brayden, David J., Imran, Muhammad, Bhattacharjee, Sourav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024478/ https://www.ncbi.nlm.nih.gov/pubmed/35456664 http://dx.doi.org/10.3390/pharmaceutics14040830

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