Cargando…

Single-Cell Sequencing: Ariadne’s Thread in the Maze of Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a haematological neoplasm resulting from the accumulation of genetic and epigenetic alterations. Patients’ prognoses vary with AML genetic heterogeneity, which hampers successful treatments. Single-cell approaches have provided new insights of the clonal architecture...

Descripción completa

Detalles Bibliográficos
Autores principales:	Redavid, Immacolata, Conserva, Maria Rosa, Anelli, Luisa, Zagaria, Antonella, Specchia, Giorgina, Musto, Pellegrino, Albano, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024495/ https://www.ncbi.nlm.nih.gov/pubmed/35454044 http://dx.doi.org/10.3390/diagnostics12040996

Ejemplares similares

RARG Gene Dysregulation in Acute Myeloid Leukemia
por: Conserva, Maria Rosa, et al.
Publicado: (2019)

Exploring the Potential of Eltrombopag: Room for More?
por: Tarantini, Francesco, et al.
Publicado: (2022)

Can the New and Old Drugs Exert an Immunomodulatory Effect in Acute Myeloid Leukemia?
por: Tarantini, Francesco, et al.
Publicado: (2021)

IKAROS in Acute Leukemia: A Positive Influencer or a Mean Hater?
por: Conserva, Maria Rosa, et al.
Publicado: (2023)

Dysregulation of miRNA in Leukemia: Exploiting miRNA Expression Profiles as Biomarkers
por: Anelli, Luisa, et al.
Publicado: (2021)

Nanopore sequencing approach for immunoglobulin gene analysis in chronic lymphocytic leukemia
por: Minervini, Crescenzio Francesco, et al.
Publicado: (2021)

The Pleiotropic Role of Retinoic Acid/Retinoic Acid Receptors Signaling: From Vitamin A Metabolism to Gene Rearrangements in Acute Promyelocytic Leukemia
por: Conserva, Maria Rosa, et al.
Publicado: (2019)

IRF4 expression is low in Philadelphia negative myeloproliferative neoplasms and is associated with a worse prognosis
por: Cumbo, Cosimo, et al.
Publicado: (2021)

Inside the biology of early T-cell precursor acute lymphoblastic leukemia: the perfect trick
por: Tarantini, Francesco, et al.
Publicado: (2021)

Case report: biallelic DNMT3A mutations in acute myeloid leukemia
por: Cumbo, Cosimo, et al.
Publicado: (2023)

The genomic analysis brings a new piece to the molecular jigsaw of idiopathic erythrocytosis
por: Zagaria, Antonella, et al.
Publicado: (2022)

Next-Generation Sequencing in Acute Lymphoblastic Leukemia
por: Coccaro, Nicoletta, et al.
Publicado: (2019)

The Role of NLRP3, a Star of Excellence in Myeloproliferative Neoplasms
por: Parciante, Elisa, et al.
Publicado: (2023)

Feasibility of Optical Genome Mapping in Cytogenetic Diagnostics of Hematological Neoplasms: A New Way to Look at DNA
por: Coccaro, Nicoletta, et al.
Publicado: (2023)

Monosomal karyotype in myeloid neoplasias: a literature review
por: Anelli, Luisa, et al.
Publicado: (2017)

SETBP1 and miR_4319 dysregulation in primary myelofibrosis progression to acute myeloid leukemia
por: Albano, Francesco, et al.
Publicado: (2012)

Nanopore Targeted Sequencing for Rapid Gene Mutations Detection in Acute Myeloid Leukemia
por: Cumbo, Cosimo, et al.
Publicado: (2019)

Skin lesions in chronic myeloid leukemia patients during dasatinib treatment
por: Tarantini, Francesco, et al.
Publicado: (2019)

SETBP1 dysregulation in congenital disorders and myeloid neoplasms
por: Coccaro, Nicoletta, et al.
Publicado: (2017)

Second Cancer Onset in Myeloproliferative Neoplasms: What, When, Why?
por: Cumbo, Cosimo, et al.
Publicado: (2022)

The JAK2 GGCC (46/1) Haplotype in Myeloproliferative Neoplasms: Causal or Random?
por: Anelli, Luisa, et al.
Publicado: (2018)

Epitranscriptomics in Normal and Malignant Hematopoiesis
por: Minervini, Crescenzio Francesco, et al.
Publicado: (2020)

Monitoring of Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia: Recent Advances
por: Cumbo, Cosimo, et al.
Publicado: (2020)

Clonal Hematopoiesis at the Crossroads of Inflammatory Bowel Diseases and Hematological Malignancies: A Biological Link?
por: Cumbo, Cosimo, et al.
Publicado: (2022)

Immunomodulatory Drugs in Acute Myeloid Leukemia Treatment
por: Piccolomo, Antonio, et al.
Publicado: (2020)

Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements
por: Albano, Francesco, et al.
Publicado: (2010)

HDV Pathogenesis: Unravelling Ariadne’s Thread
por: Tseligka, Eirini D., et al.
Publicado: (2021)

Gene expression profiling of chronic myeloid leukemia with variant t(9;22) reveals a different signature from cases with classic translocation
por: Albano, Francesco, et al.
Publicado: (2013)

HMGA Proteins in Hematological Malignancies
por: Minervini, Angela, et al.
Publicado: (2020)

TP53 in Myelodysplastic Syndromes: Recent Biological and Clinical Findings
por: Cumbo, Cosimo, et al.
Publicado: (2020)

Molecular Complexity of Diffuse Large B-Cell Lymphoma: Can It Be a Roadmap for Precision Medicine?
por: Coccaro, Nicoletta, et al.
Publicado: (2020)

Digital PCR: A Reliable Tool for Analyzing and Monitoring Hematologic Malignancies
por: Coccaro, Nicoletta, et al.
Publicado: (2020)

Nanopore Sequencing in Blood Diseases: A Wide Range of Opportunities
por: Minervini, Crescenzio Francesco, et al.
Publicado: (2020)

ADAMTS2 gene dysregulation in T/myeloid mixed phenotype acute leukemia
por: Tota, Giuseppina, et al.
Publicado: (2014)

A Crumbled but Fatal Acute Leukemia
por: Tarantini, Francesco, et al.
Publicado: (2022)

After Treatment Decrease of Bone Marrow Tregs and Outcome in Younger Patients with Newly Diagnosed Acute Myeloid Leukemia
por: Delia, Mario, et al.
Publicado: (2020)

Ariadne’s Thread in the Network of Hepatocellular Carcinoma Immunobiology
por: Koskinas, John, et al.
Publicado: (2021)

5′RUNX1-3′USP42 chimeric gene in acute myeloid leukemia can occur through an insertion mechanism rather than translocation and may be mediated by genomic segmental duplications
por: Zagaria, Antonella, et al.
Publicado: (2014)

Genomic BCR-ABL1 breakpoint characterization by a multi-strategy approach for “personalized monitoring” of residual disease in chronic myeloid leukemia patients
por: Cumbo, Cosimo, et al.
Publicado: (2018)

Pathogenicity and virulence of Mycoplasma genitalium: Unraveling Ariadne’s Thread
por: Yueyue, Wu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_np38t8nqcmgb66tmb6pej78jvl