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Detection of VAMP Proteolysis by Tetanus and Botulinum Neurotoxin Type B In Vivo with a Cleavage-Specific Antibody

Tetanus and Botulinum type B neurotoxins are bacterial metalloproteases that specifically cleave the vesicle-associated membrane protein VAMP at an identical peptide bond, resulting in inhibition of neuroexocytosis. The minute amounts of these neurotoxins commonly used in experimental animals are no...

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Detalles Bibliográficos
Autores principales:	Fabris, Federico, Šoštarić, Petra, Matak, Ivica, Binz, Thomas, Toffan, Anna, Simonato, Morena, Montecucco, Cesare, Pirazzini, Marco, Rossetto, Ornella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024618/ https://www.ncbi.nlm.nih.gov/pubmed/35457172 http://dx.doi.org/10.3390/ijms23084355

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