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Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival

Porocarcinoma is a rare malignant adnexal tumor. Little is known about the location of the disease in the head and neck. Our aim is to offer the largest analysis of demographic, pathological, and treatment patterns of head and neck porocarcinoma in comparison with other locations of the neoplasm fro...

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Autores principales: Scampa, Matteo, Merat, Rastine, Kalbermatten, Daniel F., Oranges, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024621/
https://www.ncbi.nlm.nih.gov/pubmed/35456278
http://dx.doi.org/10.3390/jcm11082185
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author Scampa, Matteo
Merat, Rastine
Kalbermatten, Daniel F.
Oranges, Carlo M.
author_facet Scampa, Matteo
Merat, Rastine
Kalbermatten, Daniel F.
Oranges, Carlo M.
author_sort Scampa, Matteo
collection PubMed
description Porocarcinoma is a rare malignant adnexal tumor. Little is known about the location of the disease in the head and neck. Our aim is to offer the largest analysis of demographic, pathological, and treatment patterns of head and neck porocarcinoma in comparison with other locations of the neoplasm from an epidemiologically representative cohort. Method: The Surveillance, Epidemiology, and End Results program of the National Cancer Institute was searched for all cases of porocarcinomas diagnosed between 2000 and 2018. This database is considered representative of the US population. Demographic, pathological, and treatment variables were compared between the head and neck and other regions. Overall and disease-specific survival was calculated and compared between groups. Results: 563 porocarcinomas were identified, with 172 in the head and neck. The mean age was 66.4 years. Males were more affected in the head and neck. Regional and distant invasion rates were low (2.9 and 2.3%, respectively). Local excision and Mohs surgery were the most frequent therapies. Five-year overall survival was 74.8%. Five-year disease-specific survival was 97%. Conclusions: Head and neck porocarcinoma affects more males than females. Regional or distant metastatic rates are low and overestimated in previous literature. Disease-specific mortality is low. Surgery remains the mainstay of treatment.
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spelling pubmed-90246212022-04-23 Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival Scampa, Matteo Merat, Rastine Kalbermatten, Daniel F. Oranges, Carlo M. J Clin Med Article Porocarcinoma is a rare malignant adnexal tumor. Little is known about the location of the disease in the head and neck. Our aim is to offer the largest analysis of demographic, pathological, and treatment patterns of head and neck porocarcinoma in comparison with other locations of the neoplasm from an epidemiologically representative cohort. Method: The Surveillance, Epidemiology, and End Results program of the National Cancer Institute was searched for all cases of porocarcinomas diagnosed between 2000 and 2018. This database is considered representative of the US population. Demographic, pathological, and treatment variables were compared between the head and neck and other regions. Overall and disease-specific survival was calculated and compared between groups. Results: 563 porocarcinomas were identified, with 172 in the head and neck. The mean age was 66.4 years. Males were more affected in the head and neck. Regional and distant invasion rates were low (2.9 and 2.3%, respectively). Local excision and Mohs surgery were the most frequent therapies. Five-year overall survival was 74.8%. Five-year disease-specific survival was 97%. Conclusions: Head and neck porocarcinoma affects more males than females. Regional or distant metastatic rates are low and overestimated in previous literature. Disease-specific mortality is low. Surgery remains the mainstay of treatment. MDPI 2022-04-14 /pmc/articles/PMC9024621/ /pubmed/35456278 http://dx.doi.org/10.3390/jcm11082185 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Scampa, Matteo
Merat, Rastine
Kalbermatten, Daniel F.
Oranges, Carlo M.
Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival
title Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival
title_full Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival
title_fullStr Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival
title_full_unstemmed Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival
title_short Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival
title_sort head and neck porocarcinoma: seer analysis of epidemiology and survival
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024621/
https://www.ncbi.nlm.nih.gov/pubmed/35456278
http://dx.doi.org/10.3390/jcm11082185
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