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Flurochloridone Induced Cell Apoptosis via ER Stress and eIF2α-ATF4/ATF6-CHOP-Bim/Bax Signaling Pathways in Mouse TM4 Sertoli Cells

Flurochloridone (FLC), as a novel herbicide, has been widely used in many countries since 1980s. Current studies have shown that FLC has toxic effects on male reproduction and its target organ is testis, while the underlying mechanism is still unknown. Mouse testis Sertoli cell line TM4 cells were u...

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Detalles Bibliográficos
Autores principales: Zhang, Fen, Ni, Zhijing, Zhao, Shuqi, Wang, Yanna, Chang, Xiuli, Zhou, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024663/
https://www.ncbi.nlm.nih.gov/pubmed/35457433
http://dx.doi.org/10.3390/ijerph19084564