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NMS-873 Leads to Dysfunctional Glycometabolism in A p97-Independent Manner in HCT116 Colon Cancer Cells

Adenosine triphosphate (ATP)–competitive p97 inhibitor CB-5339, the successor of CB-5083, is being evaluated in Phase 1 clinical trials for anti-cancer therapy. Different modes-of-action p97 inhibitors such as allosteric inhibitors are useful to overcome drug-induced resistance, one of the major pro...

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Detalles Bibliográficos
Autores principales:	Li, Shan, Wang, Feng, Zhang, Gang, Chou, Tsui-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024726/ https://www.ncbi.nlm.nih.gov/pubmed/35456598 http://dx.doi.org/10.3390/pharmaceutics14040764

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