Platelet-Derived PDGFB Promotes Recruitment of Cancer-Associated Fibroblasts, Deposition of Extracellular Matrix and Tgfβ Signaling in the Tumor Microenvironment

SIMPLE SUMMARY: The aim of this study was to investigate the relative contribution of PDGFB derived specifically from platelets to the remodeling of the extracellular matrix (ECM) in tumors. Platelets are a major source of growth factors, which are released from the platelet granules upon activation...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyu, Manouchehri Doulabi, Ehsan, Herre, Melanie, Cedervall, Jessica, Qiao, Qi, Miao, Zuoxiu, Hamidi, Anahita, Hellman, Lars, Kamali-Moghaddam, Masood, Olsson, Anna-Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024906/
https://www.ncbi.nlm.nih.gov/pubmed/35454853
http://dx.doi.org/10.3390/cancers14081947

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