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The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders

Bacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to hum...

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Autores principales: Baehren, Carolin, Buedding, Eleni, Bellm, Aliyah, Schult, Frank, Pembaur, Anton, Wirth, Stefan, Ehrhardt, Anja, Paulsen, Friedrich, Postberg, Jan, Aydin, Malik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024940/
https://www.ncbi.nlm.nih.gov/pubmed/35455967
http://dx.doi.org/10.3390/cells11081287
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author Baehren, Carolin
Buedding, Eleni
Bellm, Aliyah
Schult, Frank
Pembaur, Anton
Wirth, Stefan
Ehrhardt, Anja
Paulsen, Friedrich
Postberg, Jan
Aydin, Malik
author_facet Baehren, Carolin
Buedding, Eleni
Bellm, Aliyah
Schult, Frank
Pembaur, Anton
Wirth, Stefan
Ehrhardt, Anja
Paulsen, Friedrich
Postberg, Jan
Aydin, Malik
author_sort Baehren, Carolin
collection PubMed
description Bacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to human naso- and oropharyngeal microbiomes, i.e., bacterial microbiota, eukaryotes (mostly fungi), as well as the archaeome and their relation to respiratory and atopic disorders in infancy and adolescence. With this review, we aim to summarize state-of-the-art contributions to the field published in the last decade. In particular, we intend to build bridges between basic and clinical science.
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spelling pubmed-90249402022-04-23 The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders Baehren, Carolin Buedding, Eleni Bellm, Aliyah Schult, Frank Pembaur, Anton Wirth, Stefan Ehrhardt, Anja Paulsen, Friedrich Postberg, Jan Aydin, Malik Cells Review Bacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to human naso- and oropharyngeal microbiomes, i.e., bacterial microbiota, eukaryotes (mostly fungi), as well as the archaeome and their relation to respiratory and atopic disorders in infancy and adolescence. With this review, we aim to summarize state-of-the-art contributions to the field published in the last decade. In particular, we intend to build bridges between basic and clinical science. MDPI 2022-04-10 /pmc/articles/PMC9024940/ /pubmed/35455967 http://dx.doi.org/10.3390/cells11081287 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Baehren, Carolin
Buedding, Eleni
Bellm, Aliyah
Schult, Frank
Pembaur, Anton
Wirth, Stefan
Ehrhardt, Anja
Paulsen, Friedrich
Postberg, Jan
Aydin, Malik
The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
title The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
title_full The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
title_fullStr The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
title_full_unstemmed The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
title_short The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
title_sort relevance of the bacterial microbiome, archaeome and mycobiome in pediatric asthma and respiratory disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024940/
https://www.ncbi.nlm.nih.gov/pubmed/35455967
http://dx.doi.org/10.3390/cells11081287
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