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State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review

The need of a minimally invasive approach, especially in cases of cultural or religious oppositions to the internal examination of the body, has led over the years to the introduction of postmortem CT (PMCT) methodologies within forensic investigations for the comprehension of the cause of death in...

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Autores principales: Stassi, Chiara, Mondello, Cristina, Baldino, Gennaro, Cardia, Luigi, Gualniera, Patrizia, Calapai, Fabrizio, Sapienza, Daniela, Asmundo, Alessio, Ventura Spagnolo, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025017/
https://www.ncbi.nlm.nih.gov/pubmed/35448711
http://dx.doi.org/10.3390/tomography8020077
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author Stassi, Chiara
Mondello, Cristina
Baldino, Gennaro
Cardia, Luigi
Gualniera, Patrizia
Calapai, Fabrizio
Sapienza, Daniela
Asmundo, Alessio
Ventura Spagnolo, Elvira
author_facet Stassi, Chiara
Mondello, Cristina
Baldino, Gennaro
Cardia, Luigi
Gualniera, Patrizia
Calapai, Fabrizio
Sapienza, Daniela
Asmundo, Alessio
Ventura Spagnolo, Elvira
author_sort Stassi, Chiara
collection PubMed
description The need of a minimally invasive approach, especially in cases of cultural or religious oppositions to the internal examination of the body, has led over the years to the introduction of postmortem CT (PMCT) methodologies within forensic investigations for the comprehension of the cause of death in selected cases (e.g., traumatic deaths, acute hemorrhages, etc.), as well as for personal identification. The impossibility to yield clear information concerning the coronary arteries due to the lack of an active circulation to adequately distribute contrast agents has been subsequently overcome by the introduction of coronary-targeted PMCT Angiography (PMCTA), which has revealed useful in the detection of stenoses related to calcifications and/or atherosclerotic plaques, as well as in the suspicion of thrombosis. In parallel, due to the best ability to study the soft tissues, cardiac postmortem MR (PMMR) methodologies have been further implemented, which proved suitable for the detection and aging of infarcted areas, and for cardiomyopathies. Hence, the purpose of the present work to shed light on the state of the art concerning the value of both coronary-targeted PMCTA and PMMR in the diagnosis of coronary artery disease and/or myocardial infarction as causes of death, further evaluating their suitability as alternatives or complementary approaches to standard autopsy and histologic investigations.
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spelling pubmed-90250172022-04-23 State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review Stassi, Chiara Mondello, Cristina Baldino, Gennaro Cardia, Luigi Gualniera, Patrizia Calapai, Fabrizio Sapienza, Daniela Asmundo, Alessio Ventura Spagnolo, Elvira Tomography Review The need of a minimally invasive approach, especially in cases of cultural or religious oppositions to the internal examination of the body, has led over the years to the introduction of postmortem CT (PMCT) methodologies within forensic investigations for the comprehension of the cause of death in selected cases (e.g., traumatic deaths, acute hemorrhages, etc.), as well as for personal identification. The impossibility to yield clear information concerning the coronary arteries due to the lack of an active circulation to adequately distribute contrast agents has been subsequently overcome by the introduction of coronary-targeted PMCT Angiography (PMCTA), which has revealed useful in the detection of stenoses related to calcifications and/or atherosclerotic plaques, as well as in the suspicion of thrombosis. In parallel, due to the best ability to study the soft tissues, cardiac postmortem MR (PMMR) methodologies have been further implemented, which proved suitable for the detection and aging of infarcted areas, and for cardiomyopathies. Hence, the purpose of the present work to shed light on the state of the art concerning the value of both coronary-targeted PMCTA and PMMR in the diagnosis of coronary artery disease and/or myocardial infarction as causes of death, further evaluating their suitability as alternatives or complementary approaches to standard autopsy and histologic investigations. MDPI 2022-04-01 /pmc/articles/PMC9025017/ /pubmed/35448711 http://dx.doi.org/10.3390/tomography8020077 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Stassi, Chiara
Mondello, Cristina
Baldino, Gennaro
Cardia, Luigi
Gualniera, Patrizia
Calapai, Fabrizio
Sapienza, Daniela
Asmundo, Alessio
Ventura Spagnolo, Elvira
State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
title State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
title_full State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
title_fullStr State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
title_full_unstemmed State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
title_short State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
title_sort state of the art on the role of postmortem computed tomography angiography and magnetic resonance imaging in the diagnosis of cardiac causes of death: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025017/
https://www.ncbi.nlm.nih.gov/pubmed/35448711
http://dx.doi.org/10.3390/tomography8020077
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