Cargando…
State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review
The need of a minimally invasive approach, especially in cases of cultural or religious oppositions to the internal examination of the body, has led over the years to the introduction of postmortem CT (PMCT) methodologies within forensic investigations for the comprehension of the cause of death in...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025017/ https://www.ncbi.nlm.nih.gov/pubmed/35448711 http://dx.doi.org/10.3390/tomography8020077 |
_version_ | 1784690762452041728 |
---|---|
author | Stassi, Chiara Mondello, Cristina Baldino, Gennaro Cardia, Luigi Gualniera, Patrizia Calapai, Fabrizio Sapienza, Daniela Asmundo, Alessio Ventura Spagnolo, Elvira |
author_facet | Stassi, Chiara Mondello, Cristina Baldino, Gennaro Cardia, Luigi Gualniera, Patrizia Calapai, Fabrizio Sapienza, Daniela Asmundo, Alessio Ventura Spagnolo, Elvira |
author_sort | Stassi, Chiara |
collection | PubMed |
description | The need of a minimally invasive approach, especially in cases of cultural or religious oppositions to the internal examination of the body, has led over the years to the introduction of postmortem CT (PMCT) methodologies within forensic investigations for the comprehension of the cause of death in selected cases (e.g., traumatic deaths, acute hemorrhages, etc.), as well as for personal identification. The impossibility to yield clear information concerning the coronary arteries due to the lack of an active circulation to adequately distribute contrast agents has been subsequently overcome by the introduction of coronary-targeted PMCT Angiography (PMCTA), which has revealed useful in the detection of stenoses related to calcifications and/or atherosclerotic plaques, as well as in the suspicion of thrombosis. In parallel, due to the best ability to study the soft tissues, cardiac postmortem MR (PMMR) methodologies have been further implemented, which proved suitable for the detection and aging of infarcted areas, and for cardiomyopathies. Hence, the purpose of the present work to shed light on the state of the art concerning the value of both coronary-targeted PMCTA and PMMR in the diagnosis of coronary artery disease and/or myocardial infarction as causes of death, further evaluating their suitability as alternatives or complementary approaches to standard autopsy and histologic investigations. |
format | Online Article Text |
id | pubmed-9025017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90250172022-04-23 State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review Stassi, Chiara Mondello, Cristina Baldino, Gennaro Cardia, Luigi Gualniera, Patrizia Calapai, Fabrizio Sapienza, Daniela Asmundo, Alessio Ventura Spagnolo, Elvira Tomography Review The need of a minimally invasive approach, especially in cases of cultural or religious oppositions to the internal examination of the body, has led over the years to the introduction of postmortem CT (PMCT) methodologies within forensic investigations for the comprehension of the cause of death in selected cases (e.g., traumatic deaths, acute hemorrhages, etc.), as well as for personal identification. The impossibility to yield clear information concerning the coronary arteries due to the lack of an active circulation to adequately distribute contrast agents has been subsequently overcome by the introduction of coronary-targeted PMCT Angiography (PMCTA), which has revealed useful in the detection of stenoses related to calcifications and/or atherosclerotic plaques, as well as in the suspicion of thrombosis. In parallel, due to the best ability to study the soft tissues, cardiac postmortem MR (PMMR) methodologies have been further implemented, which proved suitable for the detection and aging of infarcted areas, and for cardiomyopathies. Hence, the purpose of the present work to shed light on the state of the art concerning the value of both coronary-targeted PMCTA and PMMR in the diagnosis of coronary artery disease and/or myocardial infarction as causes of death, further evaluating their suitability as alternatives or complementary approaches to standard autopsy and histologic investigations. MDPI 2022-04-01 /pmc/articles/PMC9025017/ /pubmed/35448711 http://dx.doi.org/10.3390/tomography8020077 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Stassi, Chiara Mondello, Cristina Baldino, Gennaro Cardia, Luigi Gualniera, Patrizia Calapai, Fabrizio Sapienza, Daniela Asmundo, Alessio Ventura Spagnolo, Elvira State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review |
title | State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review |
title_full | State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review |
title_fullStr | State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review |
title_full_unstemmed | State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review |
title_short | State of the Art on the Role of Postmortem Computed Tomography Angiography and Magnetic Resonance Imaging in the Diagnosis of Cardiac Causes of Death: A Narrative Review |
title_sort | state of the art on the role of postmortem computed tomography angiography and magnetic resonance imaging in the diagnosis of cardiac causes of death: a narrative review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025017/ https://www.ncbi.nlm.nih.gov/pubmed/35448711 http://dx.doi.org/10.3390/tomography8020077 |
work_keys_str_mv | AT stassichiara stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT mondellocristina stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT baldinogennaro stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT cardialuigi stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT gualnierapatrizia stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT calapaifabrizio stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT sapienzadaniela stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT asmundoalessio stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview AT venturaspagnoloelvira stateoftheartontheroleofpostmortemcomputedtomographyangiographyandmagneticresonanceimaginginthediagnosisofcardiaccausesofdeathanarrativereview |