Neuronal Hyperexcitability and Free Radical Toxicity in Amyotrophic Lateral Sclerosis: Established and Future Targets

Amyotrophic lateral sclerosis (ALS) is a devastating disease with evidence of degeneration involving upper and lower motor neuron compartments of the nervous system. Presently, two drugs, riluzole and edaravone, have been established as being useful in slowing disease progression in ALS. Riluzole po...

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Detalles Bibliográficos
Autores principales: Shibuya, Kazumoto, Otani, Ryo, Suzuki, Yo-ichi, Kuwabara, Satoshi, Kiernan, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025031/
https://www.ncbi.nlm.nih.gov/pubmed/35455429
http://dx.doi.org/10.3390/ph15040433

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